Muscle pain & CoQ10
Every year, approximately 1.5 million people on statin therapy are likely to develop muscle-related complications directly related to statin use. These muscle side effects range from mild myalgia (muscle pain) through to severe life-threatening rhabdomyolysis (breakdown of damaged muscle tissue which may lead to kidney failure).
Statins work by inhibiting an enzyme called HMG-CoA. When you block that enzyme you also block the production of CoQ10, a vitamin-like substance found in every body cell which serves to produce energy and act as an antioxidant. The use of statins can reduce CoQ10 levels by 16-54% and depletion of intramuscular CoQ10 has been demonstrated in mitochondrial myopathies (muscle disease). Restoring CoQ10 levels in statin patients with muscle pain may therefore provide some benefit; preliminary trials of CoQ10 supplementation have recorded evidence of its effectiveness.
If you are suffering with muscle pain which may be a result of, or exacerbated by, your statin medication, incorporate foods higher in CoQ10. Animal heart is the best food source of CoQ10, with pork heart and beef heart being particularly beneficial. If heart really isn’t your cup of tea supplement your diet with 100-200mg of Co-Q10, twice a day, with a fatty meal.
As with all medical conditions, consult with your doctor before embarking on any supplement to your normal diet.